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Why do my urinary B6 markers say I'm deficient if I'm supplementing and my plasma levels are high-normal?
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Why do my urinary B6 markers say I'm deficient if I'm supplementing and my plasma levels are high-normal?

Q&A Files #300 Early Release Podcast

Short answer: Low or low-normal alkaline phosphatase may raise the plasma B6 level over the cellular level. Tryptophan metabolites in urine reflect the B6 requirement for the kynurenine pathway, and this requirement increases with more estrogen, more inflammation, or a higher protein intake.

This is a clip from a live Q&A session open to CMJ Masterpass members. In addition to this episode, you can access five other free samples from this batch here:

Questions on Vitamin D, Fatty Liver, HbA1c vs CGM, Turmeric and Testosterone, Fasting, and B6 Markers

In that batch of free episodes you will also find the answers to these questions:

  • What's the difference between 25(OH)D and 1,25(OH)2D when it comes to the VDR?

  • Reversing Fatty Liver: How Long Does It Take?

  • What if my A1C says I'm diabetic but my CGM says I'm fine?

  • Will reishi, turmeric, or curcumin tank my testosterone?

  • The 3 Phases of Fasting: And How to Get Kicked Out of Each One

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This snippet is from the July 13 AMA. The full recording and transcript is reserved for Masterpass members. Here is a preview of what’s included:

Ask Me Anything | July 13, 2022

Glycine problems, deficiency signs when lab tests are normal, the 3 phases of fasting & what kicks you out, lipoic acid & methylation, sulfur SIBO that always comes back, heat intolerance, and more.

The questions include:

  • How do I know if my digestive enzymes are helping or hurting?

  • Why does high-dose glycine give me these terrible symptoms?

  • How to know if my magnesium is messing with my calcium?

  • Why do I have vitamin A symptoms when my lab tests are normal?

  • What is my favorite web site for finding enzymatic cofactors?

  • Potassium citrate vs potassium chloride

  • Major problems with B vitamin supplements

  • Is food sensitivity testing useful?

  • What nutrients might help with dihydropyrimidine dehydrogenase deficiency?

  • Does lipoic acid hurt methylation?

  • Sulfur SIBO that just won’t go away.

  • Using lactate, pyruvate, and ketone ratios to indicate the NADH/NAD+ ratio.

  • Helping bile flow without pharmaceuticals.

  • Managing pernicious anemia.

  • Do we really need to meet the RDA for calcium?

  • Could stretch marks be a sign of copper toxicity?

  • When iron saturation is driven by low binding capacity.

  • How do I know if I need methyl-free Bs?

  • What causes heat intolerance?

Disclaimer

I am not a medical doctor and this is not medical advice. My goal is to empower you with information. Please make all health decisions yourself, consulting sources you trust, including a caring health care professional.

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