Jan 10 • 18M

Vitamin K2 and Undercarboxylated Osteocalcin

Q&A Files #314 Early Release Podcast

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If undercarboxylated osteocalcin has health benefits, and vitamin K2 decreases it, what does that mean for K2 supplementation?

This is a question asked live during the December 14, 2022 AMA.

Short Answer: Vitamin K2 helps secure osteocalcin in bone matrix, where it is decarboxylated and released as an endocrine hormone in response to certain stimuli. When released, it acts to optimize insulin secretion, insulin sensitivity, fuel use during exercise, and male testosterone.

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This snippet is from the December 14, 2022 AMA. The full recording and transcript is reserved for Masterpass members. Here is a preview of what’s included:

Ask Me Anything | December 14 AMA

Inositol, TMAO, undercarboxylated osteocalcin, liver enzymes, heart disease, methylation and selenium, and my twitching protocol.

The questions include:

  • Inositol, What Is It Good For?

  • If I am at risk of heart disease, and phosphatidylcholine raises my TMAO, should I stop the supplement?

  • Maragen Calcium

  • Could slow methylation cause high selenium levels?

  • My current thoughts on cholesterol and heart disease

  • If I already have oxidative stress, what ducks should I have in a row before supplementing with iron?

  • Is it safe to take eight milligrams of zinc daily without copper?

  • What to do about developing sensitivities to an increasingly broad range of foods?

  • What else to do about hemochromatosis besides phlebotomy?

  • If gestational diabetes is just a biotin deficiency, why are women who are insulin resistant prior to pregnancy at higher risk for it, including women with PCOS?

  • What to do about chronically elevated amylase and lipase?

  • What to do about a non-drinker having very high GGT and occasionally high ALT?

  • What are the most common vitamin and mineral deficiencies?

  • What are the best supplements, vitamins, and minerals for OCD and depression?

  • What is the connection between low pyruvate and high ketones?

  • Is high LDL a concern if the carotid IMT and coronary calcium scan are clear?

  • An algorithm to fix twitching

  • Do I trust food allergy tests?


I am not a medical doctor and this is not medical advice. My goal is to empower you with information. Please make all health decisions yourself, consulting sources you trust, including a caring health care professional.

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