Why Should Postprandial Glucose Be Kept Under 140 mg/dL?

Question: Why should postprandial blood glucose be kept under 140 milligrams per deciliter?

This is a question asked live during the April 12, 2023 AMA.

Short Answer: When blood glucose rises above 140 mg/dL, this is the approximate point at which it spills into the polyol pathway at a greater-than-normal rate, which represents a suboptimal state of metabolism that is likely to hurt antioxidant status and compromise detoxification pathways as well as the recycling of vitamin K and folate. It must be kept in mind that a healthy person will adapt to glycemic loads they consume regularly. Thus, a one-time spike above 140 mg/dL should never be used to conclude anything whatsoever. Only repeated spikes above this level with repeated consumption of the same glycemic load over several days to several weeks should be used as a cause for concern.

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This snippet is from the April 12, 2023 AMA. The full recording and transcript is reserved for Masterpass members. Here is a preview of what’s included:

Ask Me Anything | April 12, 2023 AMA

All things heart disease, and on blood sugar, nutritional testing, oxalates, and more.

The questions include:

• What Causes Hypercholesterolemia and Does It Matter?

• How to Reverse Coronary Calcification?

• How to do a comprehensive nutritional screening

• How can I protect against oxalates?

• How long after eating improperly cooked egg whites should I wait to take biotin?

• Is the extrusion process as harmful as some claim?

• How long can one fast before micronutrient deficiencies become an issue?

• Do B vitamins compete with each other for absorption?

• Why is thirst a symptom of diabetes?

• Do I agree with Peter Attia that ApoB should be driven as low as pharmacologically possible?

• During a fast, does the body break down muscle?

• How do you rest and refeed your brain?

• Why would someone have high RBC magnesium but low serum magnesium?

• GLA deficiency?

• Should we eat for our ethnicity?

• How convincing are polyphenol studies?

• Can coronary calcium be driven by oxalate?

• Citrulline for vasodilation

• How to reduce catabolism

• Rapid-fire run-through of orphaned questions from the submission contest, including a detailed look at Nadia’s thyroid numbers

Disclaimer

I am not a medical doctor and this is not medical advice. My goal is to empower you with information. Please make all health decisions yourself, consulting sources you trust, including a caring health care professional.

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