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Glutathione Intolerance: Getting to the Bottom of It

Q&A Files #308 Early Release Video

Why do many chronically ill people have an intolerance to glutathione, and what can be done at home to determine the cause?

This is a question asked live during the October 12, 2022 AMA.

Short Answer: It could be byproducts of any of the three amino acids that make up the glutathione molecule, which include the individual amino acids, ammonia, hydrogen sulfide, sulfite, and propionyl CoA, or it could be microbial metabolites of glutathione produced in the gut. The full answer contains seven hypothesis-driven tests that can be done at home to determine the cause.

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This snippet is from the October 12, 2022 AMA. The full recording and transcript is reserved for Masterpass members. Here is a preview of what’s included:

Ask Me Anything | October 12, 2022

Statins versus sulfur, glutathione intolerance, plasma zinc, unexplained rises in urine ketones, continuous glucose monitors, MK-4 and heart palpitations, niacin forms, and more.

The questions include:

  • NADH vs NMN vs NR

  • An unexplained rise in urine ketones

  • Spreading out calcium across meals

  • What should we have in our cold season cabinet?

  • What besides diet could cause my high morning glucose on a CGM?

  • Will some older people benefit from supplementing carnitine?

  • What do I think about the CGM fad?

  • Could my low triglycerides be cholestasis?

  • Why limit the dose of cod liver oil?

  • Why do I always feel better when my sulfur problems are worse?

  • Should I use one lab’s reference range with another lab’s results?

  • Is it safe to eat roasted potatoes?

  • How much weight should I give genetic SNPs in my nutrition?

  • High RBC magnesium but low serum: what could it mean?

  • Burning in the stomach: what could it be?

  • Should I treat low plasma amino acids by supplementing them?

  • Why would MK-4 cause heart palpitations?

Disclaimer

I am not a medical doctor and this is not medical advice. My goal is to empower you with information. Please make all health decisions yourself, consulting sources you trust, including a caring health care professional.

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Authors
Chris Masterjohn, PhD