If you're referring to the Substack one-post teaser feature, I would try it in a different browser (as with everything that ever doesn't work on the internet), or, best, try it in the Substack app.
If it still doesn't work, contact Substack support, as I have no control over the feature and it is run by Substack.
Have contacted Substack and followed their protocol to open the Crohn’s link…..clear browser, different browser, clear cookies, different device, etc. nothing working. They suggested I contact you…..now we’re going in circles. Sure hope you can help us who are struggling with Crohn’s get access to this information.
I’m not sure what you mean. All the protocols are for members only. How is it possible you can see any of them without being a member? What you are describing makes no sense to me.
The protocol was never free for 24 hours. However, the link to the protocol from the protocols page was not working, and that has now been fixed.
The actual page was always working, and it went out by email and was also linked on the home page.
I found out today from a paying member that the link on the protocols page was dead, but I never suspected this from the people who were talking about a "free link" because I did not know what they were talking about and was confused.
So:
1) the link now works
2) there was never a 24-hour free period
3) Substack has a continuous promotion allowing each free subscriber to access one single premium post for free and it could include the Crohn's protocol for anyone who has not used that promotion for a different page.
If you're referring to the Substack one-post teaser feature, I would try it in a different browser (as with everything that ever doesn't work on the internet), or, best, try it in the Substack app.
If it still doesn't work, contact Substack support, as I have no control over the feature and it is run by Substack.
Yep... i have been going round in circles trying to access the Cronhns protocol and its not working... please help... i really need to help my cousin out who is suffering terribly xxx
If you're referring to the Substack one-post teaser feature, I would try it in a different browser (as with everything that ever doesn't work on the internet), or, best, try it in the Substack app.
If it still doesn't work, contact Substack support, as I have no control over the feature and it is run by Substack.
If you're referring to the Substack one-post teaser feature, I would try it in a different browser (as with everything that ever doesn't work on the internet), or, best, try it in the Substack app.
If it still doesn't work, contact Substack support, as I have no control over the feature and it is run by Substack.
If you're referring to the Substack one-post teaser feature, I would try it in a different browser (as with everything that ever doesn't work on the internet), or, best, try it in the Substack app.
If it still doesn't work, contact Substack support, as I have no control over the feature and it is run by Substack.
If you're referring to the Substack one-post teaser feature, I would try it in a different browser (as with everything that ever doesn't work on the internet), or, best, try it in the Substack app.
If it still doesn't work, contact Substack support, as I have no control over the feature and it is run by Substack.
I love your articles. I'm a Clinical Nutritionist in the UK. Have you approached the IFM to do training for them. Our members of BÀNT will really benefit from your expertise.
Hi Jennifer, I don't see that happening any time soon but I will definitely be doing training to build a network of practitioners that can use the BioOpt protocols.
Are the Sulphur and Manganese protocols meant to be both diagnostic and therapeutic? Any concerns about trying them without really knowing whether needed? I'm trying to understand root cause of muscle rigidity and frmuscnt spasms (especiallydiaphragm), but it's hard to tease out nutritional issues from neuroendocrine (and yes mitochondrial) dysfunction i have from pharma injury. Also have brain fog, so this stuff is difficult for me to truly grasp. And, if I can just try a protocol or two, can I purchase them? Or must I do as a member only? Thanks!
I am not a medical doctor, I do not practice medicine, so I do not do anything that is "diagnostic" or "therapeutic."
They are members only.
I don't think you need to know everything to try something and see if it works, so if you are hitting a wall understanding every last thing you might want to try some things based on best data-driven guesses.
No, the Cheat Sheet has some uses of it, and some of the protocols have some use of it, but I will not be producing a generic “how to use whole genome sequencing” resource as that is to vast and unwieldy of a topic to make anything that generic that is also useful.
I had a whole genome sequence because of a suspected inherited condition in my family, which I turned out not to have. I used sequencing.com because their price was competitive and they seemed quite good on privacy. They try to funnel you into a subscription so that you can be alerted when new discoveries are made that are relevant to your genome, but I wasn't interested.
There are industry standard genetic file formats, the most immediately useful of which is VCF. A human whole genome sequence VCF file from sequencing.com is 1.8GB; it's a text file, and you can browse it using a file reader designed specifically for large text files, for example this one: https://web.archive.org/web/20140908181354fw_/http://swiftgear.com/ltfviewer/features.html, so when you read in the literature about some genetic variant that you think you might have, it's quite nice to be able to look it up in your genome. You can use bioinformatics tools such as plink to convert VCF into the more compact 23andMe format, which is quite useful for uploading to various websites that will generate reports on health conditions, such as promethease.com, codegen.eu and even Chris's MTHFR analysis tool on this website, although that one wouldn't take my file because it was too large! The VCF file gradually becomes outdated, because it describes your genome relative to a specific human reference genome, and from time to time new versions of that reference genome are published, for example to correct mistakes. So it's good to future-proof your genome by keeping the BAM format file which is around 84GB and contains the raw sequencing data, which can in principle be used to build a new VCF using any reference genome that may be adopted in the future.
There are many reference websites where you can look up genetic variants, and they are maintained collectively rather like Wikipedia; one site that the general public tends to use is https://snpedia.com.
Regarding benefits of WGS, I would say they are probably not massive for most people. Most people would get more value from a decent blood test. So much of the interpretation of these genomes is on the lines of "this variant makes you X% more susceptible to cardiovascular disease but the effect can be overridden by lifestyle choices" while somewhere else in your genome you're likely to have other variants that make you Y% LESS susceptible to cardiovascular disease. Certain rare genetic disorders aside, most of the information you get from a WGS is surprisingly vague and contradictory, and a lot of the associations with disease are found in regions that don't even code for proteins, regions which are likely involved in making different cell types act differently, in ways we don't yet understand. Sequencing certainly didn't decrypt the whole of medicine in the way that people perhaps hoped it would 25-30 years ago. It's hard enough to predict what somebody even looks like from their genome; the reports I've seen like that on my own genome are hilariously wrong: wrong eye colour, wrong hair colour, apparently my genes say I'm almost certainly bald. The big healthcare charities do a lot of misdirected and fruitless genetic research, because their pharma industry donors want to develop complex patentable gene-based treatments. At some point, AI may tell us a lot more about the genome, at which point a WGS could be more interesting.
I can assure you this is definitely not the case, except maybe as a very minor contributor, because MTHFR polymorphisms are very common compared to EDS.
See my MTHFR protocol for what to do about MTHFR. Whatever is not fixed by that — or more likely by a very small amount of riboflavin alone — is definitely not caused by MTHFR.
That's very true! I only ruled out the condition (an amyloidosis that's actually pretty common) as being mediated through a particular (very rare) genetic variant.
The Crohn's link has been fixed.
Crohns link not opening.
If you're referring to the Substack one-post teaser feature, I would try it in a different browser (as with everything that ever doesn't work on the internet), or, best, try it in the Substack app.
If it still doesn't work, contact Substack support, as I have no control over the feature and it is run by Substack.
The option to purchase the COVID Protocol at this link does not allow me to “check out.” Could you provide assistance? Thank you.
https://chris-masterjohn-phd.myshopify.com/products/the-food-and-supplement-guide-for-the-coronavirus
Have contacted Substack and followed their protocol to open the Crohn’s link…..clear browser, different browser, clear cookies, different device, etc. nothing working. They suggested I contact you…..now we’re going in circles. Sure hope you can help us who are struggling with Crohn’s get access to this information.
I usually read most Substack articles in the app….also not working. Why would all the other protocol links open with no problem, but not that one?
I’m not sure what you mean. All the protocols are for members only. How is it possible you can see any of them without being a member? What you are describing makes no sense to me.
This protocol is free for 24h now, that is why he sees it.
The protocol was never free for 24 hours. However, the link to the protocol from the protocols page was not working, and that has now been fixed.
The actual page was always working, and it went out by email and was also linked on the home page.
I found out today from a paying member that the link on the protocols page was dead, but I never suspected this from the people who were talking about a "free link" because I did not know what they were talking about and was confused.
So:
1) the link now works
2) there was never a 24-hour free period
3) Substack has a continuous promotion allowing each free subscriber to access one single premium post for free and it could include the Crohn's protocol for anyone who has not used that promotion for a different page.
Also having trouble opening the Crohns protocol. Would love to help my Crohns.
If you're referring to the Substack one-post teaser feature, I would try it in a different browser (as with everything that ever doesn't work on the internet), or, best, try it in the Substack app.
If it still doesn't work, contact Substack support, as I have no control over the feature and it is run by Substack.
Yep... i have been going round in circles trying to access the Cronhns protocol and its not working... please help... i really need to help my cousin out who is suffering terribly xxx
If you're referring to the Substack one-post teaser feature, I would try it in a different browser (as with everything that ever doesn't work on the internet), or, best, try it in the Substack app.
If it still doesn't work, contact Substack support, as I have no control over the feature and it is run by Substack.
Free link to the Crohns post doesn’t open
If you're referring to the Substack one-post teaser feature, I would try it in a different browser (as with everything that ever doesn't work on the internet), or, best, try it in the Substack app.
If it still doesn't work, contact Substack support, as I have no control over the feature and it is run by Substack.
Yes, Crohn’s protocol was not working for me either…….🫤
If you're referring to the Substack one-post teaser feature, I would try it in a different browser (as with everything that ever doesn't work on the internet), or, best, try it in the Substack app.
If it still doesn't work, contact Substack support, as I have no control over the feature and it is run by Substack.
The link for the Crohn's protocol doesn't seem to work...? It was the one I was most interested in, so would much like to see it...
If you're referring to the Substack one-post teaser feature, I would try it in a different browser (as with everything that ever doesn't work on the internet), or, best, try it in the Substack app.
If it still doesn't work, contact Substack support, as I have no control over the feature and it is run by Substack.
I'll give that a go...
I love your articles. I'm a Clinical Nutritionist in the UK. Have you approached the IFM to do training for them. Our members of BÀNT will really benefit from your expertise.
Hi Jennifer, I don't see that happening any time soon but I will definitely be doing training to build a network of practitioners that can use the BioOpt protocols.
Are the Sulphur and Manganese protocols meant to be both diagnostic and therapeutic? Any concerns about trying them without really knowing whether needed? I'm trying to understand root cause of muscle rigidity and frmuscnt spasms (especiallydiaphragm), but it's hard to tease out nutritional issues from neuroendocrine (and yes mitochondrial) dysfunction i have from pharma injury. Also have brain fog, so this stuff is difficult for me to truly grasp. And, if I can just try a protocol or two, can I purchase them? Or must I do as a member only? Thanks!
I am not a medical doctor, I do not practice medicine, so I do not do anything that is "diagnostic" or "therapeutic."
They are members only.
I don't think you need to know everything to try something and see if it works, so if you are hitting a wall understanding every last thing you might want to try some things based on best data-driven guesses.
Hi Chris- Can you give some more information about the Whole Genome Sequencing you recommend? Do you have a link or any video discussing the benefits?
No, the Cheat Sheet has some uses of it, and some of the protocols have some use of it, but I will not be producing a generic “how to use whole genome sequencing” resource as that is to vast and unwieldy of a topic to make anything that generic that is also useful.
I had a whole genome sequence because of a suspected inherited condition in my family, which I turned out not to have. I used sequencing.com because their price was competitive and they seemed quite good on privacy. They try to funnel you into a subscription so that you can be alerted when new discoveries are made that are relevant to your genome, but I wasn't interested.
There are industry standard genetic file formats, the most immediately useful of which is VCF. A human whole genome sequence VCF file from sequencing.com is 1.8GB; it's a text file, and you can browse it using a file reader designed specifically for large text files, for example this one: https://web.archive.org/web/20140908181354fw_/http://swiftgear.com/ltfviewer/features.html, so when you read in the literature about some genetic variant that you think you might have, it's quite nice to be able to look it up in your genome. You can use bioinformatics tools such as plink to convert VCF into the more compact 23andMe format, which is quite useful for uploading to various websites that will generate reports on health conditions, such as promethease.com, codegen.eu and even Chris's MTHFR analysis tool on this website, although that one wouldn't take my file because it was too large! The VCF file gradually becomes outdated, because it describes your genome relative to a specific human reference genome, and from time to time new versions of that reference genome are published, for example to correct mistakes. So it's good to future-proof your genome by keeping the BAM format file which is around 84GB and contains the raw sequencing data, which can in principle be used to build a new VCF using any reference genome that may be adopted in the future.
There are many reference websites where you can look up genetic variants, and they are maintained collectively rather like Wikipedia; one site that the general public tends to use is https://snpedia.com.
Regarding benefits of WGS, I would say they are probably not massive for most people. Most people would get more value from a decent blood test. So much of the interpretation of these genomes is on the lines of "this variant makes you X% more susceptible to cardiovascular disease but the effect can be overridden by lifestyle choices" while somewhere else in your genome you're likely to have other variants that make you Y% LESS susceptible to cardiovascular disease. Certain rare genetic disorders aside, most of the information you get from a WGS is surprisingly vague and contradictory, and a lot of the associations with disease are found in regions that don't even code for proteins, regions which are likely involved in making different cell types act differently, in ways we don't yet understand. Sequencing certainly didn't decrypt the whole of medicine in the way that people perhaps hoped it would 25-30 years ago. It's hard enough to predict what somebody even looks like from their genome; the reports I've seen like that on my own genome are hilariously wrong: wrong eye colour, wrong hair colour, apparently my genes say I'm almost certainly bald. The big healthcare charities do a lot of misdirected and fruitless genetic research, because their pharma industry donors want to develop complex patentable gene-based treatments. At some point, AI may tell us a lot more about the genome, at which point a WGS could be more interesting.
You cannot rule out a condition with WGS.
https://news.tulane.edu/pr/could-vitamin-deficiency-cause-%E2%80%98double-jointedness%E2%80%99-and-troubling-connective-tissue-disorder
Most likely ehlers danos is caused by MTHFR. Can we infer that people with MTHFR have some level of problem with collagen? If so, what should we do?
I just discovered that I have MTHFR and my knees have been dislocating since I was six.
I can assure you this is definitely not the case, except maybe as a very minor contributor, because MTHFR polymorphisms are very common compared to EDS.
See my MTHFR protocol for what to do about MTHFR. Whatever is not fixed by that — or more likely by a very small amount of riboflavin alone — is definitely not caused by MTHFR.
That's very true! I only ruled out the condition (an amyloidosis that's actually pretty common) as being mediated through a particular (very rare) genetic variant.
Right, and and you didn’t rule out that you had a different rare variant, perhaps one not even documented yet, in the same gene.