Great timing Chris, thanks for this special on Moly. Just this Saturday I got blood work finished for plasma aminos and have been perplexed about some of these sulfurs, thinking I need molybdenum.
Why would Methionine be a strong 85%, Glutathione a strong 80%, but Cyst(i)ne sub 20% with no cystathionine activity? My B6/9/12 is great but it would appear to me at least that instead of being recycled into Meth the spent methionine is all going to Taurine which is literally off the charts. All I can think of, besides a full genome test, is that I have too many sulfurs and could use some Moly.
I will at least try your suggestion in the last article about home-testing for it but this has been quite puzzling. Most other aminos are average and I want to start adding substantial protein (urea is 1%) but I'm not sure if that's a great idea until this is resolved.
Bonus, is sulfur acidic? Ketones came out at 10 and I've been burping more than anyone I know. Somehow I believe the two are related but IDK it could be off-topic. Maybe it was an idea worth raising because I read somewhere that Taurine has some functions related to fats.
I'm assuming that supplementing sulfur containing amino acids (Taurine, Cysteine) and Alpha Lipoic acid would also increase Molybdenum requirement, right?
“it dramatically enhances the metallothionein response to mercury, so it could interact with heavy metals to chelate zinc and copper.”
I thought MT used Zinc and Copper to chelate mercury - why would enhanced MT response to mercury chelate our Zinc and Copper? Or is this alluding to them being used up by MT, in the process of chelating Mercury?
Gaat dit en ook Kindle beschikbaar vanuit Holland? Heeft u toevallig ook een nederlandse vertaling? Ik wil al heel lang molybdeen aanschaffen , echter nog niet gedaan vanwege onzeker over dat ik er dan ook koper en zink bij moet nemen waarschijnlijk. Heb het vermoeden dat mijn zwavelpaden niet optimaal werken. En ik eet ruim vlees ennelke dag kool (ivm salycilaat en oxalaat, histamine in andere groentes). En wat kost een abonnement bij u?
I've been testing urine pH with and without supplemental Molybdenum - no change. I eat some beans and no liver, but apparently am not deficient in M, or at least my body doesn't use supplemental M to detox sulfite and increase Net Renal Acid Load (NRAL).
I have noticed big swings in urine pH from diet changes. Eating foods high in organic acids like tart apples and orange juice makes a big difference.
Could there be a scenario in which home-testing with PH does not show a deficiency, but Molybdenum supplementation still benefits testosterone production?
In reply to Ali---Well I actually don't know. But I always thought it could be an indication of excessive oxidative stress from some process metals or other toxic or pathogenic exposure possibly straining glutathione production and using up molybdenum... not withstanding genetic (or acting dirty - hat tip Dr Lynch for this expression) SNPs in various related pathways... but Masterjohn points to a dietary connection of excess sulfur based amino acids from a carnivore diet, if I am reading him correctly. But as it turns out the professional I consulted with Dr Nuzum was correct in his assertion as an hair trace mineral analysis - htma - did show excessive mercury and cadmium. He said these metals compete for the same receptor site and that this could explain why my loved one seems stirred up when she takes NAC, a precursor that is sulfur based to glutathione. As it would be dislodging mercury from this receptor site potentially. So I give my loved one binders... and have asked about xeolite attenuating ... molybdenum deficiency related to a heavy metal exposure... but I haven't heard anything.
It also turns out that my loved one did have low molybdenum on her htma analysis too. I do supplement her with molybdenum in a multi and if I give her NAC.
I think I will check her progress with a repeat test since it has been about a year since she had one.
Also I think molybdenum has shown some potential in breast cancer research iirc.
the practice of teasing a topic, molybdenum in this case, and then hiding the most important info behind an "upgrade to paid" button is not nice, but hey, we all need money, me too. But coming from someone whose book (Vitamins and Minerals 101) I bought in a pre-release version what, 4 years ago? 5? and never got it, it makes me increasingly angry and I feel screwed
Why people might be deficient in molybdenum for instance? Heavy metal toxicity... with mercury or cadmium? I askrd this question to an expert and his first reply was heavy metal toxicity to those specific metals lower sulfur... and this affects molybdenum too if I understood correctly.
What whole food or supplemental substances food can or might attenuate... a deficiency due to this possible exposure? What other things might cause a molybdenum deficiency?
Such as I found it interesting to note that molybdenum is found in zeolites.
Might zeolite help attenuate a deficiency or a surplus?
Great timing Chris, thanks for this special on Moly. Just this Saturday I got blood work finished for plasma aminos and have been perplexed about some of these sulfurs, thinking I need molybdenum.
Why would Methionine be a strong 85%, Glutathione a strong 80%, but Cyst(i)ne sub 20% with no cystathionine activity? My B6/9/12 is great but it would appear to me at least that instead of being recycled into Meth the spent methionine is all going to Taurine which is literally off the charts. All I can think of, besides a full genome test, is that I have too many sulfurs and could use some Moly.
I will at least try your suggestion in the last article about home-testing for it but this has been quite puzzling. Most other aminos are average and I want to start adding substantial protein (urea is 1%) but I'm not sure if that's a great idea until this is resolved.
Bonus, is sulfur acidic? Ketones came out at 10 and I've been burping more than anyone I know. Somehow I believe the two are related but IDK it could be off-topic. Maybe it was an idea worth raising because I read somewhere that Taurine has some functions related to fats.
I'm assuming that supplementing sulfur containing amino acids (Taurine, Cysteine) and Alpha Lipoic acid would also increase Molybdenum requirement, right?
Great post! I love eating lentils and split peas often for molybdenum, manganese, folate and some other nutrients.
Would you say the most important nutrients for night blindness are molybdenum and vitamin A?
I’m confused by this passage here
“it dramatically enhances the metallothionein response to mercury, so it could interact with heavy metals to chelate zinc and copper.”
I thought MT used Zinc and Copper to chelate mercury - why would enhanced MT response to mercury chelate our Zinc and Copper? Or is this alluding to them being used up by MT, in the process of chelating Mercury?
Hi hi, ik zou graag de spiekbrief kopen.
Gaat dit en ook Kindle beschikbaar vanuit Holland? Heeft u toevallig ook een nederlandse vertaling? Ik wil al heel lang molybdeen aanschaffen , echter nog niet gedaan vanwege onzeker over dat ik er dan ook koper en zink bij moet nemen waarschijnlijk. Heb het vermoeden dat mijn zwavelpaden niet optimaal werken. En ik eet ruim vlees ennelke dag kool (ivm salycilaat en oxalaat, histamine in andere groentes). En wat kost een abonnement bij u?
Dank.
Kind regards, Patricia (patty on twitter)
I've been testing urine pH with and without supplemental Molybdenum - no change. I eat some beans and no liver, but apparently am not deficient in M, or at least my body doesn't use supplemental M to detox sulfite and increase Net Renal Acid Load (NRAL).
I have noticed big swings in urine pH from diet changes. Eating foods high in organic acids like tart apples and orange juice makes a big difference.
Impact of Molybdenum Compounds as Anticancer Agents
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754869/
Could there be a scenario in which home-testing with PH does not show a deficiency, but Molybdenum supplementation still benefits testosterone production?
In reply to Ali---Well I actually don't know. But I always thought it could be an indication of excessive oxidative stress from some process metals or other toxic or pathogenic exposure possibly straining glutathione production and using up molybdenum... not withstanding genetic (or acting dirty - hat tip Dr Lynch for this expression) SNPs in various related pathways... but Masterjohn points to a dietary connection of excess sulfur based amino acids from a carnivore diet, if I am reading him correctly. But as it turns out the professional I consulted with Dr Nuzum was correct in his assertion as an hair trace mineral analysis - htma - did show excessive mercury and cadmium. He said these metals compete for the same receptor site and that this could explain why my loved one seems stirred up when she takes NAC, a precursor that is sulfur based to glutathione. As it would be dislodging mercury from this receptor site potentially. So I give my loved one binders... and have asked about xeolite attenuating ... molybdenum deficiency related to a heavy metal exposure... but I haven't heard anything.
It also turns out that my loved one did have low molybdenum on her htma analysis too. I do supplement her with molybdenum in a multi and if I give her NAC.
I think I will check her progress with a repeat test since it has been about a year since she had one.
Also I think molybdenum has shown some potential in breast cancer research iirc.
Sugar corrects testosterone really nicely - and thyroid and metabolic function
the practice of teasing a topic, molybdenum in this case, and then hiding the most important info behind an "upgrade to paid" button is not nice, but hey, we all need money, me too. But coming from someone whose book (Vitamins and Minerals 101) I bought in a pre-release version what, 4 years ago? 5? and never got it, it makes me increasingly angry and I feel screwed
Why people might be deficient in molybdenum for instance? Heavy metal toxicity... with mercury or cadmium? I askrd this question to an expert and his first reply was heavy metal toxicity to those specific metals lower sulfur... and this affects molybdenum too if I understood correctly.
What whole food or supplemental substances food can or might attenuate... a deficiency due to this possible exposure? What other things might cause a molybdenum deficiency?
Such as I found it interesting to note that molybdenum is found in zeolites.
Might zeolite help attenuate a deficiency or a surplus?
Thank you for all you do.