9 Comments
User's avatar
Michael Hood's avatar

Thanks for these informative updates, and thanks for letting us know that you have updated the CoQ10 article!

Expand full comment
RT's avatar

Yea I appreciate the thoroughness @chris!

Expand full comment
Lori's avatar

The subject of manganese has interested me for many years. I have a theory but I cannot prove it. I have had a lifelong problem keeping my iron and ferritin levels normal. My ferritin drops rapidly anytime I am not actively supplementing with iron. I also have one gene for hemochromatosis, but I was also told that would have no impact on my health ever. Well, I know how hard I have struggled with this baffling iron issue – – I am way past menopause. I shouldn’t be needing supplemental iron, but I do. My theory is that that hemachromatosis gene just makes my body’s ability to handle iron wonky. And now after years of supplementing, my manganese is very low per my hair and blood tests. I am working on this with foods like pineapple, tea and coffee, but I understand it is an antagonistic relationship with iron.

To complicated a little more, I was hospitalized with mercury poisoning 35 years ago, and at that time I was told that the mechanism for mercury was to block the action of manganese. So I spent the next two years trying to excrete the mercury with supplemental manganese. It was a long and difficult recovery, and maybe that wasn’t even the problem. But I do know that when my manganese levels came up my mercury symptoms finally abated.

Expand full comment
Chris Masterjohn, PhD's avatar

This absolutely sounds like you have impaired ferroportin or DMT1.

Expand full comment
Lighted's avatar

Interesting. I was As, Hg, Pb poisoned around 2013 and spent 6 months @ 1/2hr in FIRed sauna. Collected my sweat and urine one day and sent to Hill Laboratory and was stunned at amount of these 3 elements in the sweat compared to urine. I have a high Ferritin @241 on last test and have been donating blood monthly (i am on wrong side of 60). Last blood dark field was not too flash either. I wont give up beef as this is the only meat i eat but I would like ferritin down a bit towards normal. I have lethargy and metabolic syndrone despite intermitent fasting (18:6) and very low carb diet.

Expand full comment
Lighted's avatar

Glysophate binds Cu, Mn and Zn. I believe urine can be tested for either glyphosate or an analogue.

Expand full comment
Peter Ahlering's avatar

Is there any new content on this site? No new articles or audio!?! What do we pay for?

Expand full comment
User's avatar
Comment deleted
Mar 12, 2024
Comment deleted
Expand full comment
Chris Masterjohn, PhD's avatar

CoQ10 doesn’t abolish statin myopathy, and statins likely decrease CoQ10 entry into the brain.

Expand full comment