While maybe you are right that NAC alone will mess up your gut, maybe nac + glycine has only benefits. There should be a better study on it, fair enough, but the results from that study in my opinion are amazing. Also maybe adding extra zinc+vit A will help the gut and balance the problems NAC could potentially do. Or just go lower dose, not 10g/day but 5g would still provide good benefits i assume. I think we live in world where we need all the extra help we can get, just like the vit D+A+K2 articles that you had ( and videos ) where people are protected from parasites/infections and have better calcium flux, or the high thiamine doses that EOnutrition talks about, it's clear that we need extra help in a shitty world.
"you wouldn't take any supplement for longer periods of time" but we have fortified foods for quite some time and iodine added to salt so.. we kinda need it
I am willing to consider any hypotheses about NAC interaction, but you essentially listed a number of postulations without any hypotheses to support their plausibility. Why would glycine prevent NAC from thinning mucous? How would it do that?
I agree we all need a little help, but fortified foods do not use high doses of things, and it I in the high doses where trouble can come into play.
People who succeed with Overton’s message are probably disproportionately impacted by genetically impaired pyruvate dehydrogenase.
I avoid fortified foods and I do take supplements, but my supplements long term are food-based or they have specific targeted purposes.
As I said in the video, it is the acute dose, not the chronic dose, of NAC that is relevant. So it’s far more important that the dose is spread out than whether it is 5 or 10 g per day.
While maybe you are right that NAC alone will mess up your gut, maybe nac + glycine has only benefits. There should be a better study on it, fair enough, but the results from that study in my opinion are amazing. Also maybe adding extra zinc+vit A will help the gut and balance the problems NAC could potentially do. Or just go lower dose, not 10g/day but 5g would still provide good benefits i assume. I think we live in world where we need all the extra help we can get, just like the vit D+A+K2 articles that you had ( and videos ) where people are protected from parasites/infections and have better calcium flux, or the high thiamine doses that EOnutrition talks about, it's clear that we need extra help in a shitty world.
"you wouldn't take any supplement for longer periods of time" but we have fortified foods for quite some time and iodine added to salt so.. we kinda need it
It is unlikely that anything “has only benefits.”
I am willing to consider any hypotheses about NAC interaction, but you essentially listed a number of postulations without any hypotheses to support their plausibility. Why would glycine prevent NAC from thinning mucous? How would it do that?
I agree we all need a little help, but fortified foods do not use high doses of things, and it I in the high doses where trouble can come into play.
People who succeed with Overton’s message are probably disproportionately impacted by genetically impaired pyruvate dehydrogenase.
I avoid fortified foods and I do take supplements, but my supplements long term are food-based or they have specific targeted purposes.
As I said in the video, it is the acute dose, not the chronic dose, of NAC that is relevant. So it’s far more important that the dose is spread out than whether it is 5 or 10 g per day.