60 Comments
Feb 29Liked by Chris Masterjohn, PhD

I have been saying this for years- and running Nutreval on all my patients- I have seen the trend too much- elevations in glyceric and glycolic- this is why the low ox diet is not working as much as you expected! Thank you for making this clear.

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Feb 29Liked by Chris Masterjohn, PhD

Yes!! Thank you for that! 5 years ago, so ill I could no longer work. Mostly Carnivore 4 1/2 yrs, better all the time and still learning what helps and what doesn't. Educating more on DNA polymorphisms.

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Feb 29Liked by Chris Masterjohn, PhD

Thank you so much Chris. You've been so helpful in understanding my oxalate situation and I am eager to perform the genetic testing soon.

I've tested high on a 24 hour oxalate test at Kaiser and 401.69 mmol/mol creatine on a glycolic acid Vibrant Wellness OAT. My citric acid cycle was tanked and I suffered from Candidiasis but this went away when I went carnivore and cut out fruits and vegetables. I've read that candida uses oxalate as a substrate to build biofilms. I have been dumping 3-5 times a day for the last year; It's sucked but I am finally feeling better.

Supplementing with sulfate and molybdenum has helped tremendously as oxalate displaces sulfate, and vice versa, via the SAT-1 transport protein in a concentration dependent manner.

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Feb 29Liked by Chris Masterjohn, PhD

Definitely going to reduce oxalates further and see if I find a difference and good to be motivated to avoid seed oils as part of the same effort. I've read Sally Norton but not really made a full scale effort so far.

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Mar 1Liked by Chris Masterjohn, PhD

This was super-helpful and very timely. I've seen a huge improvement in certain symptoms I *thought* were caused by oxalates after removing the major known sources of PUFAs from my diet.

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Feb 29Liked by Chris Masterjohn, PhD

Thank you Chris for another brilliant article.

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Feb 29Liked by Chris Masterjohn, PhD

Great stuff

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Feb 29·edited Feb 29

I ditched seed oils over a decade ago, yet my OAT shows urinary oxalic level beyond the upper limit at 72 mmol/mol creatine. I have high levels of B12 and biotin, and I have been supplementing B6 for 6+ months yet I am low in B6 and glutathione (which may be due to genetic predisposals). I’m currently looking into eliminating high oxalate foods from my diet, especially wild-gathered greens!

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Feb 29·edited Feb 29

It seems to me that most Vitamin E products on the market are dosed substantially higher than your recommendation (not as insanely as most B-Vitamins, but still). What are the risk with too high Vitamin E?

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I think I feel oxalates on my teeth when I eat spinach or chard ( but not chocolate or sweet potatoes which are also high in it). Does that happen to anyone else and does it mean anything?

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Is a urine oxalate test reliable? does it correlate with tissue levels (which is where they become a problem, right?), or otherwise is there a good way of testing?

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Feb 29·edited Mar 1

Chris as always I love your work. Please contact me. I have been trying to reconnect with you after a 2022 purchase of consulting package. I experienced serious delays, and we are finally in pre-launch stages for a system that among other things filters out oxalates, displays oxalates in recipes and tracks oxalates when our menu planning app is used. I wanted to consult with you pre-launch. But have found my old contacts for you no longer working. Please contact here https://primallynourished.com/contactUs and I will get back to you. ASAP.

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Would krill or black seed oil be a better choice than fish oil?

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How I wish your recommendations worked for Australians! I’d upgrade in a heartbeat!

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Hey Chris, you mentioned copper ions in the article as part of the mechanism of lipid peroxidation. Does this mean that in those with high copper levels (as per a blood test for example) that they are at higher risk of oxalate overload (if the PUFA is high enough)?

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Hello, thanks for the article. I read that hot pepper seeds also have oxalates, peppers have less oxalates than fatty seeds? Thank you

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