Introduction
Supplementation does increase the acylcarnitine fraction and total carnitine to near normal levels. But I'm not clear about whether it's worth worrying about. So, if the total carnitine is low, but the free carnitine is normal, then total carnitine is low because the acylcarnitines are low. I wouldn't be too worried about the acylcarnitines being low. I would be very worried if the acylcarnitines were very high and overwhelming the total pool of carnitine, 'cause that would suggest a metabolic problem.
This Q&A can also be found as part of a much longer episode, here:
080: Ask Me Anything About Nutrition, December 2, 2020
DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.
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