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179: What’s the difference between the NADH/NAD+ and the NADPH/NADH ratios?

Masterjohn Q&A Files Episode 179


Question: What’s the difference between the NADH/NAD+ and the NADPH/NADH ratios?

So the NADH to NAD ratio and the NAD pH to NADP plus ratio are things that are having real consequences as ratios and biochemistry that are dictating what's going on in our body. The NAD pH to NADH ratio is physiologically irrelevant, but is used as a biomarker of niacin status. So if you look at a biochemistry textbook, that's telling you how things work in the body you're going to see constant references to the NADH to NAD ratio or the NAD pH NADP plus ratio. And you're never going to see any reference to the NAD pH to NADH ratio.

This Q&A can also be found as part of a much longer episode, here:

080: Ask Me Anything About Nutrition, December 2, 2020

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DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

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The Masterjohn Q&A Files
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Chris Masterjohn, PhD