102: Why does estrogen regulate tryptophan metabolism
Masterjohn Q&A Files Episode 102
Chris: I think that it's basically the body trying to make sure that the baby has enough niacin because chronic estrogen exposure would occur during pregnancy. When I was doing my niacin research, one thing that I found is that women seem to need more total niacin than men, but they seem to be better at making niacin from protein. What's really interesting is that the studies that were done that were used to make the RDA, there weren't comparisons in men and women, but two of the studies were men and two studies were in women. The standard deviations, meaning how much variation there was person to person, in how much niacin that they needed to normalize what they were looking at was way bigger in men than it was in women.
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DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.
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