100: The use of pregnenolone to manage perimenopausal symptoms, particularly insomnia.

Masterjohn Q&A Files Episode 100

Introduction

Carrie: Well, so here's the thing about pregnenolone. Oral or sublingual, so if you've got drops or little tables you suck on. Pregnenolone and progesterone, when they go through first pass, so you swallow them and then you go through first pass, they turn into other metabolites. One is called allo, which is short for allopregnanolone. Allo binds to your GABA receptors in your brain. Allo can cross the blood-brain barrier, binds to GABA. GABA, of course, is your calming, relaxing, everything is going to be okay hormone. Pregnenolone, oral pregnenolone and oral progesterone actually work on the anxiety and on the insomnia from a GABA point of view.

This Q&A can also be found as part of a much longer episode, here:

Harnessing the Power of Nutrients
050: Ask Us Anything About Hormones with Dr. Carrie Jones | May 10, 2019
Watch now (125 min) | On May 10, members of the CMJ Masterpass joined me and Dr. Carrie Jones in a live Zoom meeting to ask us anything about hormones, and here’s the full recording! We talk about things like: What time of day is best to take T4 and/or T3? How to use pregnenolone to manage perimenopausal insomnia…
Read more

If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up with a 10% lifetime discount here: https://chrismasterjohnphd.com/q&a

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DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

PLEASE NOTE: As a result of the COVID-19 crisis and the time I am committing to staying on top of relevant research, as well as the high volume of questions I receive, it may take me extra time to respond to questions here. For an up-to-date list of where I respond to questions most quickly, please see the contact page on chrismasterjohnphd.com.

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