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092: Are bilirubin and uric acid useful markers of antioxidant defense and oxidative stress? What are better markers?

Masterjohn Q&A Files Episode 92


I think the best marker of oxidative stress in plasma is the cysteine to cystine ratio. Cysteine is the reduced form of the amino acid cysteine. Cystine is the oxidized form. There are good studies at a general population level showing that that is the major specific indicator of oxidative stress that takes place in the plasma.

So, what I would recommend to assess oxidative stress would be Genova's Oxidative Stress 2.0 panel. It does give you the cysteine to cystine ratio.

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The Masterjohn Q&A Files
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Chris Masterjohn, PhD