049: Pantothenic Acid, Part 2 (Foods, Lab Tests, and Supplements)

Mastering Nutrition Episode 49

Show Notes

01:14 Recap of Part 1

06:39 Cliff Notes

08:53 The case for why urinary pantothenic acid is the only legitimate marker of nutritional status and why blood concentration is not a useful marker

22:25 How the Adequate Intake for pantothenic acid was established

23:44 The idea of pantothenic acid balance and comparing it to nitrogen balance

35:40 What I think the recommended pantothenic acid intake should be

39:08 The effect of different forms of food processing on loss of B5 from foods

44:23 Dietary sources of B5, divided into five tiers

48:13 The contribution of the gastrointestinal microbiome to B5 status

01:00:14 Causes of suboptimal status or deficiency of pantothenic acid

01:06:01 Prevalence of suboptimal pantothenic acid status

01:06:34 When I think supplementation with high doses is warranted

01:07:12 What are some of the benefits, besides fixing deficiency, that we might get from supplementing with pantothenic acid or its derivatives?

01:07:28 The use of pantethine as a therapeutic for dyslipidemia

01:17:03 Comparison of pantethine supplementation to high-dose niacin for lowering blood lipids

01:19:35 Topical dexpanthenol for skin health and wound healing

01:23:15 The effect of pantothenic acid supplementation on acne

01:26:44 The effect of pantothenic acid supplementation on sports performance

01:35:00 The effect of pantothenic acid supplementation on hair health

01:36:36 The effect of pantothenic acid supplementation on arthritis

01:42:33 Summary of pantothenic acid supplementation

01:46:30 Is there any reason to use pantothenic acid specifically versus other forms such as pantethine?

01:48:51 Does it matter if you take pantothenic acid in divided doses or all at once?

01:51:10 Does it matter if you take pantothenic acid with food?

01:52:53 Two insightful quotes from papers on pantothenic acid

01:58:10 Pantothenate should be known as the B vitamin that we know the least about, not the B vitamin that we are least likely to become deficient in.

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