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064: Can you give any suggestions for increasing delta-6 desaturase activity?

Masterjohn Q&A Files Episode 64


Can you give any suggestions for increasing delta-6 desaturase activity?

The big governor though is if you have if you have insulin resistance or you have low insulin levels from chronic carbohydrate restriction, that might increase it. But you also look at your inflammation because you might have some of the higher fatty acids being depleted from inflammation or oxidative stress. I mean, more nutrient-dense diet across the board, more carbohydrate, if that doesn't do it, then just maybe take a supplement or increase the liver and egg yolks to the point where the arachidonic acid is normal. Measure your CRP. If that's high, address inflammation.

In the Testing Nutritional Status: The Ultimate Cheat Sheet, I have a big section on oxidative stress. I go through that testing. A starting point might be Genova's Oxidative Stress 2.0 blood panel. But if inflammation and oxidative stress are the things, work on those. If those aren't issues, then more nutrient density across the board, fix any nutrient deficiencies you find, increase carbohydrate if you're on low-carb. If none of those things work, then just increase your arachidonic acid level in your diet.

This Q&A can also be found as part of a much longer episode, here:

Harnessing the Power of Nutrients
Recording and Transcript of Ask Me Anything About Nutrition | February 23, 2019
Watch now (148 min) | Below you will find the time stamps for specific questions, the relevant links, the private podcast audio version, and the transcript. The time stamps are available to everyone but everything else is reserved for Masterpass members. Learn more about the Masterpass…
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The Masterjohn Q&A Files
We use Zoom, a video chatting software, in webinar mode. You can ask your question anonymously in text, but you can also ask it publicly, and you can even get "on stage" and share your mic, web cam, or screen with everyone.
Chris Masterjohn, PhD