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044: Nutritional strategies for glucose 6-phosphate dehydrogenase (G6PDH) deficiency.

Masterjohn Q&A Files Episode 44


Question: What are the best ways to optimize glutathione status for someone who has a G6PD deficiency?

Riboflavin was shown to be of benefit for normalizing oxidative stress in people who have glucose 6-phosphate dehydrogenase deficiency.

So for people who don't know what this is G6PD is, glucose 6-phosphate dehydrogenase is an enzyme that you use to take energy from glucose specifically, you can't take it from anything else, and you use it to recycle glutathione which is a master antioxidant of the cell. 

You also need this to support the recycling of vitamin K and folate and you need this for synthesis of neurotransmitters among other things.

What I would usually recommend for glutathione status would be plasma levels of glutathione. I also think LabCorp does whole blood glutathione.

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The Masterjohn Q&A Files
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Chris Masterjohn, PhD