Methylene Blue: Biohacker's delight, or playing with fire?

The winner of the July Question Contest is about methylene blue.

I have summarized it as follows:

Methylene Blue: Biohacker’s Delight? Or Playing With Fire?

Methylene blue as a pure solid, where it appears greenish.

Mixed in in a solvent such as water, methyelene blue takes on its characteristic blue color.

What You Will Find Below

• Short Answer

• Downloads

• Methylene Blue in Ten Minutes

• The Origin of Methylene Blue

• The Entry of Methylene Blue Into Medicine

• From Malaria to Many Uses in Medicine

• How Methylene Blue Works

  • A Redox-Reactive Dye

  • The Blue Bottle Experiment

  • Methylene Blue Radicals, Photoexcited States, and Demethylated Metabolites

  • Methylene Blue Can Oxidize and Reduce Many Targets

  • Methylene Blue Can Rewire the Mitochondrial Respiratory Chain

  • Rewiring the Respiratory Chain Does Not Make It Better

  • Methylene Blue Increases Hydrogen Peroxide

  • Hydrogen Peroxide Kills Microbes, Has Hormetic Benefits, But Is Still Ultimately Toxic

  • Methylene Blue Causes Redox Cycling of Hemoglobin

  • Methylene Blue Is a Strong Monoamine Oxidase A Inhibitor

  • Methylene Blue Inhibits Nitric Oxide Synthase

  • Mechanistic Conclusions

• Is Methylene Blue Fundamentally Hormetic?

• Methylene Blue Fails in Alzheimer’s, and Causes a Worrisome Side Effect

• Whether Methylene Blue Helps Or Hurts Depends on Whether You Need It

• Natural Alternatives for Hormesis and Rewiring the Respiratory Chain

• Who Should Use Methylene Blue?

The downloadable PDF is now free to everyone here. Masterpass members have access to the web page version and the ten-minute condensed audio and video podcast below.