Does Erythritol Cause Heart Disease?

This analysis of the recent study by the Hazen group at Cleveland Clinic published in Nature Medicine claiming erythritol contributes to cardiovascular disease shows the following:

1) Why elevated plasma erythritol is likely to reflect thiamin deficiency and NADPH depletion from insulin resistance, inflammation, and oxidative stress

2) Why the in vitro and mouse study blood clotting likely reflects osmotic stress with no relevance to the use of erythritol as a sweetener.

3) Why I strongly suspect the Hazen group is hiding data, specifically the data that they obviously had a chance to collect and would have clinched their case but appears nowhere in their paper.

4) Why even though I do not use erythritol as a sweetener, were I ever to think about doing so, the new Nature Medicine paper would play no role in my decision.

Read the analysis in written form, fully referenced, here:

Harnessing the Power of Nutrients
Erythritol and Blood Clotting
Masterpass members have access to a monthly Q&A that includes a question submission contest, and one of runners up for tonight’s AMA asked me to take a look at the new study in Nature Medicine tying erythritol levels to cardiovascular risk. This is brought to us by the Hazen group at Cleveland Clinic, the folks who brought to us the research tying TMAO t…
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Authors
Chris Masterjohn, PhD