319: What cofactors are needed to synthesize and recycle BH4?
Masterjohn Q&A Files Episode 319
Question: What cofactors are needed to synthesize and recycle BH4?
Short Answer: Zinc, magnesium, potassium, and niacin are the cofactors needed for the synthesis and recycling of BH4. Folate and methylation are not involved, though high-dose folate or folic acid could hypothetically hurt BH4 recycling since both are recycled by dihydrofolate reductase (DHFR).
This episode was cut from the original Q&A session that you can find here.
DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.
Listen to the Audio
I highly recommend watching the video above but you can also listen to the audio here: